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Identification of erythroferrone as an erythroid regulator of iron metabolism

Identification of erythroferrone as an erythroid regulator of iron metabolism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4104984

Identification of erythroferrone as an erythroid regulator of iron metabolism

About this item

Full title

Identification of erythroferrone as an erythroid regulator of iron metabolism

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2014-07, Vol.46 (7), p.678-684

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Tomas Ganz and colleagues identify a new regulator of iron metabolism, erythroferrone, that is produced by erythroblasts in response to erythropoietin and suppresses hepcidin expression during stress erythropoiesis. They further show that erythroferrone levels are highly elevated in a mouse model of β-thalassemia, contributing to hepcidin suppressi...

Alternative Titles

Full title

Identification of erythroferrone as an erythroid regulator of iron metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4104984

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4104984

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.2996

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