Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
About this item
Full title
Author / Creator
Haberman, Yael , Tickle, Timothy L , Dexheimer, Phillip J , Kim, Mi-Ok , Tang, Dora , Karns, Rebekah , Baldassano, Robert N , Noe, Joshua D , Rosh, Joel , Markowitz, James , Heyman, Melvin B , Griffiths, Anne M , Crandall, Wallace V , Mack, David R , Baker, Susan S , Huttenhower, Curtis , Keljo, David J , Hyams, Jeffrey S , Kugathasan, Subra , Walters, Thomas D , Aronow, Bruce , Xavier, Ramnik J , Gevers, Dirk and Denson, Lee A
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Interactions between the host and gut microbial community likely contribute to Crohn disease (CD) pathogenesis; however, direct evidence for these interactions at the onset of disease is lacking. Here, we characterized the global pattern of ileal gene expression and the ileal microbial community in 359 treatment-naive pediatric patients with CD, pa...
Alternative Titles
Full title
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
Authors, Artists and Contributors
Author / Creator
Tickle, Timothy L
Dexheimer, Phillip J
Kim, Mi-Ok
Tang, Dora
Karns, Rebekah
Baldassano, Robert N
Noe, Joshua D
Rosh, Joel
Markowitz, James
Heyman, Melvin B
Griffiths, Anne M
Crandall, Wallace V
Mack, David R
Baker, Susan S
Huttenhower, Curtis
Keljo, David J
Hyams, Jeffrey S
Kugathasan, Subra
Walters, Thomas D
Aronow, Bruce
Xavier, Ramnik J
Gevers, Dirk
Denson, Lee A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109533
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109533
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI75436
