Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
About this item
Full title
Author / Creator
Haberman, Yael , Tickle, Timothy L. , Dexheimer, Phillip J. , Kim, Mi-Ok , Tang, Dora , Karns, Rebekah , Baldassano, Robert N. , Noe, Joshua D. , Rosh, Joel , Markowitz, James , Heyman, Melvin B. , Griffiths, Anne M. , Crandall, Wallace V. , Mack, David R. , Baker, Susan S. , Huttenhower, Curtis , Keljo, David J. , Hyams, Jeffrey S. , Kugathasan, Subra , Walters, Thomas D. , Aronow, Bruce , Xavier, Ramnik J. , Gevers, Dirk and Denson, Lee A.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Interactions between the host and gut microbial community likely contribute to Crohn disease (CD) pathogenesis; however, direct evidence for these interactions at the onset of disease is lacking. Here, we characterized the global pattern of ileal gene expression and the ileal microbial community in 359 treatment-naive pediatric patients with CD, pa...
Alternative Titles
Full title
Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature
Authors, Artists and Contributors
Author / Creator
Tickle, Timothy L.
Dexheimer, Phillip J.
Kim, Mi-Ok
Tang, Dora
Karns, Rebekah
Baldassano, Robert N.
Noe, Joshua D.
Rosh, Joel
Markowitz, James
Heyman, Melvin B.
Griffiths, Anne M.
Crandall, Wallace V.
Mack, David R.
Baker, Susan S.
Huttenhower, Curtis
Keljo, David J.
Hyams, Jeffrey S.
Kugathasan, Subra
Walters, Thomas D.
Aronow, Bruce
Xavier, Ramnik J.
Gevers, Dirk
Denson, Lee A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109533
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109533
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI75436
