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The cystine/glutamate antiporter: when too much of a good thing goes bad

The cystine/glutamate antiporter: when too much of a good thing goes bad

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109541

The cystine/glutamate antiporter: when too much of a good thing goes bad

About this item

Full title

The cystine/glutamate antiporter: when too much of a good thing goes bad

Author / Creator

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2014-08, Vol.124 (8), p.3279-3281

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Glutamate excitotoxicity represents a major cellular component of ischemic brain injury. In this issue of the JCI, Soria and colleagues reveal that the cystine/glutamate exchanger is an important source of excitotoxic glutamate in response to ischemia induced by oxygen and glucose deprivation. As the exchanger is a primary determinant of both extra...

Alternative Titles

Full title

The cystine/glutamate antiporter: when too much of a good thing goes bad

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109541

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109541

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI76627

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