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Neurotrophic factor GDNF promotes survival of salivary stem cells

Neurotrophic factor GDNF promotes survival of salivary stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109543

Neurotrophic factor GDNF promotes survival of salivary stem cells

About this item

Full title

Neurotrophic factor GDNF promotes survival of salivary stem cells

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2014-08, Vol.124 (8), p.3364-3377

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Stem cell-based regenerative therapy is a promising treatment for head and neck cancer patients that suffer from chronic dry mouth (xerostomia) due to salivary gland injury from radiation therapy. Current xerostomia therapies only provide temporary symptom relief, while permanent restoration of salivary function is not currently feasible. Here, we...

Alternative Titles

Full title

Neurotrophic factor GDNF promotes survival of salivary stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109543

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4109543

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI74096

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