Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoart...
Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoarthritis
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Publisher
England: Elsevier Limited
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Language
English
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England: Elsevier Limited
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Background Increased subchondral bone turnover may contribute to pain in osteoarthritis (OA). Objectives To investigate the analgesic potential of a modified version of osteoprotegerin (osteoprotegerin-Fc (OPG-Fc)) in the monosodium iodoacetate (MIA) model of OA pain. Methods Male Sprague Dawley rats (140–260 g) were treated with either OPG-Fc (3 m...
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Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoarthritis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4112443
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4112443
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ISSN
0003-4967
E-ISSN
1468-2060
DOI
10.1136/annrheumdis-2013-203260