Relative importance of redox buffers GSH and NAD(P)H in age‐related neurodegeneration and Alzheimer...
Relative importance of redox buffers GSH and NAD(P)H in age‐related neurodegeneration and Alzheimer disease‐like mouse neurons
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England: John Wiley & Sons, Inc
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English
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England: John Wiley & Sons, Inc
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Summary
Aging, a major risk factor in Alzheimer's disease (AD), is associated with an oxidative redox shift, decreased redox buffer protection, and increased free radical reactive oxygen species (ROS) generation, probably linked to mitochondrial dysfunction. While NADH is the ultimate electron donor for many redox reactions, including oxidative...
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Relative importance of redox buffers GSH and NAD(P)H in age‐related neurodegeneration and Alzheimer disease‐like mouse neurons
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4116450
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4116450
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ISSN
1474-9718
E-ISSN
1474-9726
DOI
10.1111/acel.12216
