TET=catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites
TET=catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites
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Author / Creator
Yang, Hui , Lin, Huaipeng , Xu, Haiyan , Zhang, Lei , Cheng, Lu , Wen, Bo , Shou, Jianyong , Guan, Kunliang , Xiong, Yue and Ye, Dan
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
DNA methylation suppresses gene expression and plays a broad and important role in diverse biological processes such as development and tumor suppression [ 1, 2]. DNA methylation is generally thought to be relatively stable and heritable. This view is recently changed by the discovery of TET (ten-eleven translocation) family of dioxygenases which c...
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Full title
TET=catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4123294
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4123294
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ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2014.81