DrugTargetSeqR: a genomics- and CRISPR-Cas9–based method to analyze drug targets
DrugTargetSeqR: a genomics- and CRISPR-Cas9–based method to analyze drug targets
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Finding the biological targets of small molecules remains an important challenge in chemical biology and drug discovery. A method involving high-throughput sequencing, mutational analysis and clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 genome editing identifies the targets and potential modes of compound resistance for t...
Alternative Titles
Full title
DrugTargetSeqR: a genomics- and CRISPR-Cas9–based method to analyze drug targets
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4123312
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4123312
Other Identifiers
ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.1551
