Modeling tumor–host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor...
Modeling tumor–host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy
About this item
Full title
Author / Creator
Herman, S E M , Sun, X , McAuley, E M , Hsieh, M M , Pittaluga, S , Raffeld, M , Liu, D , Keyvanfar, K , Chapman, C M , Chen, J , Buggy, J J , Aue, G , Tisdale, J F , Pérez-Galán, P and Wiestner, A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Chronic lymphocytic leukemia (CLL) cells depend on microenvironmental factors for proliferation and survival. In particular, the B-cell receptor (BCR) and nuclear factor- κB (NF-κB) pathways are activated in the lymph node (LN) microenvironment. Thus, model systems mimicking tumor–host interactions are important tools to study CLL biology and patho...
Alternative Titles
Full title
Modeling tumor–host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4126654
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4126654
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2013.131
