Disruption of HPV16-E7 by CRISPR/Cas System Induces Apoptosis and Growth Inhibition in HPV16 Positiv...
Disruption of HPV16-E7 by CRISPR/Cas System Induces Apoptosis and Growth Inhibition in HPV16 Positive Human Cervical Cancer Cells
About this item
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Author / Creator
Zhu, Da , Yu, Lan , Hu, Zheng , Ding, Wencheng , Wang, Xiaoli , Zhang, Changlin , Wang, Liming , Jiang, Xiaohui , Shen, Hui , He, Dan , Li, Kezhen , Xi, Ling , Ma, Ding and Wang, Hui
Publisher
Cairo, Egypt: Hindawi Puplishing Corporation
Journal title
Language
English
Formats
Publication information
Publisher
Cairo, Egypt: Hindawi Puplishing Corporation
Subjects
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Scope and Contents
Contents
High-risk human papillomavirus (HR-HPV) has been recognized as a major causative agent for cervical cancer. Upon HPV infection, early genes E6 and E7 play important roles in maintaining malignant phenotype of cervical cancer cells. By using clustered regularly interspaced short palindromic repeats- (CRISPR-) associated protein system (CRISPR/Cas sy...
Alternative Titles
Full title
Disruption of HPV16-E7 by CRISPR/Cas System Induces Apoptosis and Growth Inhibition in HPV16 Positive Human Cervical Cancer Cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4127252
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4127252
Other Identifiers
ISSN
2314-6133
E-ISSN
2314-6141
DOI
10.1155/2014/612823
