Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation
Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
In mice, it is possible to induce a psoriasis-like condition by applying imiquimod; here, the production of interleukin-23 that is stimulated by such skin inflammation is shown to depend on the interaction of nociceptors expressing the Na
v
1.8 and TRPV1 channels with skin-resident dendritic cells.
Peripheral neurons involved in inflammati...
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Full title
Nociceptive sensory neurons drive interleukin-23-mediated psoriasiform skin inflammation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4127885
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4127885
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13199
