Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implicatio...
Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Evading apoptosis is a hallmark of B-cell chronic lymphocytic leukemia (CLL) cells and an obstacle to current chemotherapeutic approaches. Inhibiting histone deacetylase (HDAC) has emerged as a promising strategy to induce cell death in malignant cells. We have previously reported that the HDAC inhibitor MGCD0103 induces CLL cell death by activatin...
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Disruption of autophagy by the histone deacetylase inhibitor MGCD0103 and its therapeutic implication in B-cell chronic lymphocytic leukemia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4131250
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4131250
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2014.19
