Inhibition of miR-25 improves cardiac contractility in the failing heart
Inhibition of miR-25 improves cardiac contractility in the failing heart
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Reduced activity of the calcium-transporting ATPase SERCA2a is a hallmark of heart failure; here, microRNAs that downregulate SERCA2a function are identified, and antagonism of one,
miR-25
, is shown to halt heart failure in mice.
Blocking
miR-25
boosts failing heart
Chronic heart failure occurs when the cardiac muscles steadily l...
Alternative Titles
Full title
Inhibition of miR-25 improves cardiac contractility in the failing heart
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4131725
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4131725
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13073
