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Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer

Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4135724

Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer

About this item

Full title

Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2014-06, Vol.510 (7506), p.552-555

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Several proteins localized at membrane contact sites contain an SMP domain, which has been proposed to act as a lipid-binding module; here, the crystal structure of a fragment of the extended synaptotagmin 2 protein, including its SMP, is presented, and indicates that this protein may have a direct role in lipid transport.
Growing evidence sugge...

Alternative Titles

Full title

Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4135724

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4135724

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature13269

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