Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer
Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Several proteins localized at membrane contact sites contain an SMP domain, which has been proposed to act as a lipid-binding module; here, the crystal structure of a fragment of the extended synaptotagmin 2 protein, including its SMP, is presented, and indicates that this protein may have a direct role in lipid transport.
Growing evidence sugge...
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Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4135724
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4135724
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13269