Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and...
Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Changes in the stability of microtubules regulate many biological processes, but their role in memory remains unclear. Here we show that learning causes biphasic changes in the microtubule-associated network in the hippocampus. In the early phase, stathmin is dephosphorylated, enhancing its microtubule-destabilizing activity by promoting stathmin-t...
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Full title
Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4137320
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4137320
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms5389
