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Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones

Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4142213

Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones

About this item

Full title

Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2014-07, Vol.511 (7507), p.94-98

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The discovery of a selective, physiologically active inhibitor of insulin-degrading enzyme (IDE) illuminates the therapeutic potential of IDE inhibitors for the treatment of diabetes and reveals that IDE regulates
in vivo
glucagon and amylin, in addition to insulin.
An alternative approach to diabetes
Established treatments for type-2 d...

Alternative Titles

Full title

Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4142213

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4142213

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature13297

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