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HIV-1 Expression Within Resting CD4⁺ T Cells After Multiple Doses of Vorinostat

HIV-1 Expression Within Resting CD4⁺ T Cells After Multiple Doses of Vorinostat

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4148603

HIV-1 Expression Within Resting CD4⁺ T Cells After Multiple Doses of Vorinostat

About this item

Full title

HIV-1 Expression Within Resting CD4⁺ T Cells After Multiple Doses of Vorinostat

Publisher

Oxford: Oxford University Press

Journal title

The Journal of infectious diseases, 2014-09, Vol.210 (5), p.728-735

Language

English

Formats

Publication information

Publisher

Oxford: Oxford University Press

More information

Scope and Contents

Contents

Background. A single dose of the histone deacetylase inhibitor vorinostat (VOR) up-regulates HIV RNA expression within resting CD4⁺ T cells of treated, aviremic human immunodeficiency virus (HIV)-positive participants. The ability of multiple exposures to VOR to repeatedly disrupt latency has not been directly measured, to our knowledge. Methods. F...

Alternative Titles

Full title

HIV-1 Expression Within Resting CD4⁺ T Cells After Multiple Doses of Vorinostat

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4148603

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4148603

Other Identifiers

ISSN

0022-1899

E-ISSN

1537-6613

DOI

10.1093/infdis/jiu155

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