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The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthriti...

The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthriti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4151522

The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis

About this item

Full title

The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis

Publisher

England: Elsevier Limited

Journal title

Annals of the rheumatic diseases, 2014-03, Vol.73 (3), p.600-608

Language

English

Formats

Publication information

Publisher

England: Elsevier Limited

More information

Scope and Contents

Contents

Objective The histamine H4 receptor (H4R) has been shown to drive inflammatory responses in models of asthma, colitis and dermatitis, and in these models it appears to affect both innate and adaptive immune responses. In this study, we used both H4R-deficient mice and a specific H4R antagonist, JNJ 28307474, to investigate the involvement of the H4...

Alternative Titles

Full title

The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4151522

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4151522

Other Identifiers

ISSN

0003-4967

E-ISSN

1468-2060

DOI

10.1136/annrheumdis-2013-203832

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