Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
ten Berge and colleagues show that Wnt signalling is required for self-renewal of embryonic stem cells through inhibition of their differentiation into epiblast stem cells. Together, Wnt and LIF signalling can support derivation and self-renewal of embryonic stem cells.
Pluripotent stem cells exist in naive and primed states, epitomized by mouse...
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Full title
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4157727
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4157727
Other Identifiers
ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb2314
