Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell...
Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell death
About this item
Full title
Author / Creator
Dowding, J M , Song, W , Bossy, K , Karakoti, A , Kumar, A , Kim, A , Bossy, B , Seal, S , Ellisman, M H , Perkins, G , Self, W T and Bossy-Wetzel, E
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Evidence indicates that nitrosative stress and mitochondrial dysfunction participate in the pathogenesis of Alzheimer’s disease (AD). Amyloid beta (A
β
) and peroxynitrite induce mitochondrial fragmentation and neuronal cell death by abnormal activation of dynamin-related protein 1 (DRP1), a large GTPase that regulates mitochondrial fission....
Alternative Titles
Full title
Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell death
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4158687
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4158687
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2014.72
