RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis
About this item
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Author / Creator
Orozco, S , Yatim, N , Werner, M R , Tran, H , Gunja, S Y , Tait, S WG , Albert, M L , Green, D R and Oberst, A
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Necroptosis is a form of programmed cell death that depends on the activation of receptor interacting protein kinase-1 (RIPK1) and RIPK3 by receptors such as tumor necrosis factor (TNF) receptor-1. Structural studies indicate that activation of RIPK3 by RIPK1 involves the formation of oligomers via interactions of the RIP homotypic interaction moti...
Alternative Titles
Full title
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis
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Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4158689
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4158689
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2014.76
