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Antibacterial membrane attack by a pore-forming intestinal C-type lectin

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4160023

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

About this item

Full title

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2014-01, Vol.505 (7481), p.103-107

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Secreted C-type lectins protect the intestinal epithelium from Gram-positive bacteria; this study shows that for the C-type lectin RegIIIα, bacterial killing occurs in a two-step process whereby the lectin first binds to bacterial peptidoglycans then oligomerizes on the bacterial membrane to form a permeabilizing pore.
Antibacterial protein mech...

Alternative Titles

Full title

Antibacterial membrane attack by a pore-forming intestinal C-type lectin

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4160023

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4160023

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature12729

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