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Efficient Induction of Point Mutations Allowing Recovery of Specific Locus Mutations in Zebrafish

Efficient Induction of Point Mutations Allowing Recovery of Specific Locus Mutations in Zebrafish

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_41629

Efficient Induction of Point Mutations Allowing Recovery of Specific Locus Mutations in Zebrafish

About this item

Full title

Efficient Induction of Point Mutations Allowing Recovery of Specific Locus Mutations in Zebrafish

Publisher

United States: National Academy of Sciences of the United States of America

Journal title

Proceedings of the National Academy of Sciences - PNAS, 1995-06, Vol.92 (13), p.5997-6001

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences of the United States of America

More information

Scope and Contents

Contents

A technique is described that greatly increases the efficiency of recovering specific locus point mutations in zebrafish (Danio rerio). Founder individuals that were mosaic for point mutations were produced by mutagenizing postmeiotic gametes with the alkylating agent N-ethyl-N-nitrosourea. Under optimal conditions, each founder carried an average...

Alternative Titles

Full title

Efficient Induction of Point Mutations Allowing Recovery of Specific Locus Mutations in Zebrafish

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_41629

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_41629

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.92.13.5997

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