Unraveling the clonal hierarchy of somatic genomic aberrations
Unraveling the clonal hierarchy of somatic genomic aberrations
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Defining the chronology of molecular alterations may identify milestones in carcinogenesis. To unravel the temporal evolution of aberrations from clinical tumors, we developed CLONET, which upon estimation of tumor admixture and ploidy infers the clonal hierarchy of genomic aberrations. Comparative analysis across 100 sequenced genomes from prostat...
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Full title
Unraveling the clonal hierarchy of somatic genomic aberrations
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4167267
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4167267
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ISSN
1474-760X,1474-7596
E-ISSN
1474-760X
DOI
10.1186/s13059-014-0439-6
