Aberrant Production of Tenascin-C in Globoid Cell Leukodystrophy Alters Psychosine-Induced Microglia...
Aberrant Production of Tenascin-C in Globoid Cell Leukodystrophy Alters Psychosine-Induced Microglial Functions
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England: by American Association of Neuropathologists, Inc
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English
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England: by American Association of Neuropathologists, Inc
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ABSTRACTGloboid cell leukodystrophy (GLD), or Krabbe disease, is a rare and often fatal demyelinating disease caused by mutations in the galactocerebrosidase (galc) gene that result in accumulation of galactosylsphingosine (psychosine). We recently reported that the extracellular matrix (ECM) protease, matrix metalloproteinase-3, is elevated in GLD...
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Full title
Aberrant Production of Tenascin-C in Globoid Cell Leukodystrophy Alters Psychosine-Induced Microglial Functions
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4169335
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4169335
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ISSN
0022-3069
E-ISSN
1554-6578
DOI
10.1097/NEN.0000000000000117
