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Chemically Defined and Small Molecule-Based Generation of Human Cardiomyocytes

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Chemically Defined and Small Molecule-Based Generation of Human Cardiomyocytes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4169698

Chemically Defined and Small Molecule-Based Generation of Human Cardiomyocytes

About this item

Full title

Chemically Defined and Small Molecule-Based Generation of Human Cardiomyocytes

Author / Creator

Burridge, Paul W. , Matsa, Elena , Shukla, Praveen , Lin, Ziliang C. , Churko, Jared M. , Ebert, Antje D. , Lan, Feng , Diecke, Sebastian , Huber, Bruno , Mordwinkin, Nicholas M. , Plews, Jordan R. , Abilez, Oscar J. , Cui, Bianxiao , Gold, Joseph D. and Wu, Joseph C.

Journal title

Nature methods, 2014-06, Vol.11 (8), p.855-860

Language

English

Formats

Articles

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Scope and Contents

Contents

Existing methodologies for human induced pluripotent stem cell (hiPSC) cardiac differentiation are efficient but require the use of complex, undefined medium constituents that hinder further elucidation of the molecular mechanisms of cardiomyogenesis. Using hiPSCs derived under chemically defined conditions on synthetic matrices, we systematically...

Alternative Titles

Full title

Chemically Defined and Small Molecule-Based Generation of Human Cardiomyocytes

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4169698

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4169698

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/nmeth.2999

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