Differential triggering of spontaneous glutamate release by P/Q-, N- and R-type Ca2+ channels
Differential triggering of spontaneous glutamate release by P/Q-, N- and R-type Ca2+ channels
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
This study shows that spontaneous opening of presynaptic voltage-gated calcium channels (VGCCs) is a major trigger of action potential independent synaptic vesicle release, and finds that R-type channels contribute disproportionately, consistent with a relatively negative activation threshold. The authors also use Ca
2+
chelation experiments...
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Full title
Differential triggering of spontaneous glutamate release by P/Q-, N- and R-type Ca2+ channels
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4176737
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4176737
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3563
