The Scc2–Scc4 complex acts in sister chromatid cohesion and transcriptional regulation by maintainin...
The Scc2–Scc4 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Frank Uhlmann and colleagues show that the yeast Scc2–Scc4 cohesin loader complex is recruited to nucleosome-free regions in the promoters of highly expressed genes by the RSC chromatin remodeling complex and acts to maintain the nucleosome-free status of its binding sites. These findings suggest that human disorders caused by disruption of cohesin...
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The Scc2–Scc4 complex acts in sister chromatid cohesion and transcriptional regulation by maintaining nucleosome-free regions
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4177232
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4177232
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ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3080
