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Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells

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Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4178211

Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells

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England: BioMed Central Ltd

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Contents

Aerobic glycolysis, namely the Warburg effect, is the main hallmark of cancer cells. Mitochondrial respiratory dysfunction has been proposed to be one of the major causes for such glycolytic shift. This hypothesis has been revisited as tumors appear to undergo waves of gene regulation during progression, some of which rely on functional mitochondri...

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Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4178211

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4178211

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ISSN

2049-3002

E-ISSN

2049-3002

DOI

10.1186/2049-3002-1-11

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