T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance
T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance
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Publisher
Alexandria, VA: American Diabetes Association
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Language
English
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Publisher
Alexandria, VA: American Diabetes Association
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Contents
A key pathophysiologic role for activated T-cells in mediating adipose inflammation and insulin resistance (IR) has been recently postulated. However, mechanisms underlying their activation are poorly understood. In this study, we demonstrated a previously unrecognized homeostatic role for the costimulatory B7 molecules (CD80 and CD86) in preventin...
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Full title
T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4179314
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4179314
Other Identifiers
ISSN
0012-1797
E-ISSN
1939-327X
DOI
10.2337/db13-1094