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T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4179314

T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

About this item

Full title

T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

Publisher

Alexandria, VA: American Diabetes Association

Journal title

Diabetes (New York, N.Y.), 2014-04, Vol.63 (4), p.1289-1302

Language

English

Formats

Publication information

Publisher

Alexandria, VA: American Diabetes Association

More information

Scope and Contents

Contents

A key pathophysiologic role for activated T-cells in mediating adipose inflammation and insulin resistance (IR) has been recently postulated. However, mechanisms underlying their activation are poorly understood. In this study, we demonstrated a previously unrecognized homeostatic role for the costimulatory B7 molecules (CD80 and CD86) in preventin...

Alternative Titles

Full title

T-Cell Costimulation Protects Obesity-Induced Adipose Inflammation and Insulin Resistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4179314

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4179314

Other Identifiers

ISSN

0012-1797

E-ISSN

1939-327X

DOI

10.2337/db13-1094

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