SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells
SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells
About this item
Full title
Author / Creator
Santini, R , Pietrobono, S , Pandolfi, S , Montagnani, V , D'Amico, M , Penachioni, J Y , Vinci, M C , Borgognoni, L and Stecca, B
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Melanoma is one of the most aggressive types of human cancer, characterized by enhanced heterogeneity and resistance to conventional therapy at advanced stages. We and others have previously shown that HEDGEHOG-GLI (HH-GLI) signaling is required for melanoma growth and for survival and expansion of melanoma-initiating cells (MICs). Recent reports i...
Alternative Titles
Full title
SOX2 regulates self-renewal and tumorigenicity of human melanoma-initiating cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4180644
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4180644
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2014.71
