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Nuclear factor κB inhibition reduces lung vascular lumen obliteration in severe pulmonary hypertensi...

Nuclear factor κB inhibition reduces lung vascular lumen obliteration in severe pulmonary hypertensi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4189489

Nuclear factor κB inhibition reduces lung vascular lumen obliteration in severe pulmonary hypertension in rats

About this item

Full title

Nuclear factor κB inhibition reduces lung vascular lumen obliteration in severe pulmonary hypertension in rats

Publisher

United States: American Thoracic Society

Journal title

American journal of respiratory cell and molecular biology, 2014-09, Vol.51 (3), p.413-425

Language

English

Formats

Publication information

Publisher

United States: American Thoracic Society

More information

Scope and Contents

Contents

NF-κB and IL-6, a NF-κB downstream mediator, play a central role in the inflammatory response of tissues. We aimed to determine the role of the classical NF-κB pathway in severe pulmonary arterial hypertension (PAH) induced by SU5416 and chronic hypoxia (SuHx) in rats. Tissue samples from patients with idiopathic PAH (iPAH) and control subjects wer...

Alternative Titles

Full title

Nuclear factor κB inhibition reduces lung vascular lumen obliteration in severe pulmonary hypertension in rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4189489

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4189489

Other Identifiers

ISSN

1044-1549

E-ISSN

1535-4989

DOI

10.1165/rcmb.2013-0355OC

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