5[variant prime]RUNX1-3[variant prime]USP42 chimeric gene in acute myeloid leukemia can occur throug...
5[variant prime]RUNX1-3[variant prime]USP42 chimeric gene in acute myeloid leukemia can occur through an insertion mechanism rather than translocation and may be mediated by genomic segmental duplications
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London: BioMed Central
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English
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London: BioMed Central
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Doc number: 66 Abstract Background: The runt-related transcription factor 1 (RUNX1 ) gene is a transcription factor that acts as a master regulator of hematopoiesis and represents one of the most frequent targets of chromosomal rearrangements in human leukemias. The t(7;21)(p22;q22) rearrangement generating a 5[variant prime]RUNX1-3[variant prime]U...
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Full title
5[variant prime]RUNX1-3[variant prime]USP42 chimeric gene in acute myeloid leukemia can occur through an insertion mechanism rather than translocation and may be mediated by genomic segmental duplications
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4189616
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4189616
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ISSN
1755-8166
E-ISSN
1755-8166
DOI
10.1186/s13039-014-0066-7
