Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis
Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
The NF-κB signaling pathway is implicated in various inflammatory diseases, including rheumatoid arthritis (RA); therefore, inhibition of this pathway has the potential to ameliorate an array of inflammatory diseases. Given that NF-κB signaling is critical for many immune cell functions, systemic blockade of this pathway may lead to detrimental sid...
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Full title
Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4191028
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4191028
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI75673