Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop
Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Self-reactive CD4 T cells are thought to have a central role in the pathogenesis of many chronic inflammatory human diseases. Microbial peptides can activate self-reactive T cells, but the structural basis for such crossreactivity is not well understood. The Hy.1B11 T cell receptor (TCR) originates from a patient with multiple sclerosis and recogni...
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Full title
Crossreactivity of a human autoimmune TCR is dominated by a single TCR loop
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4193804
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4193804
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms3623
