Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning
Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
This study uses single-cell real-time imaging to show that sonic hedgehog (SHH) is produced in the form of a particle that is transported along a novel class of specialized actin-based filopodia spanning several cell diameters within the field of SHH cell signalling, thus expanding our knowledge of ligand movement during normal vertebrate developme...
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Full title
Specialized filopodia direct long-range transport of SHH during vertebrate tissue patterning
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4197975
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4197975
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature12157
