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Structural mechanism of glutamate receptor activation and desensitization

Structural mechanism of glutamate receptor activation and desensitization

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4199900

Structural mechanism of glutamate receptor activation and desensitization

About this item

Full title

Structural mechanism of glutamate receptor activation and desensitization

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2014-10, Vol.514 (7522), p.328-334

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Ionotropic glutamate receptors are ligand-gated ion channels that mediate excitatory synaptic transmission in the vertebrate brain. To gain a better understanding of how structural changes gate ion flux across the membrane, we trapped rat AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) and kainate receptor subtypes in their major funct...

Alternative Titles

Full title

Structural mechanism of glutamate receptor activation and desensitization

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4199900

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4199900

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature13603

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