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AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4201502

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

About this item

Full title

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

Publisher

Waltham, MA: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2014-09, Vol.371 (11), p.1028-1038

Language

English

Formats

Publication information

Publisher

Waltham, MA: Massachusetts Medical Society

More information

Scope and Contents

Contents

Enzalutamide and abiraterone target the androgen receptor and androgen synthesis and are used to treat castration-resistant prostate cancer. A splice variant of the androgen receptor is associated with resistance to both drugs.
It is now accepted that castration-resistant prostate cancer is not androgen-independent and continues to rely on andro...

Alternative Titles

Full title

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4201502

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4201502

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1315815

How to access this item