eIF4AIII enhances translation of nuclear cap-binding complex–bound mRNAs by promoting disruption of...
eIF4AIII enhances translation of nuclear cap-binding complex–bound mRNAs by promoting disruption of secondary structures in 5′UTR
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Publisher
National Academy of Sciences
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Language
English
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National Academy of Sciences
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Contents
It has long been considered that intron-containing (spliced) mRNAs are translationally more active than intronless mRNAs (identical mRNA not produced by splicing). The splicing-dependent translational enhancement is mediated, in part, by the exon junction complex (EJC). Nonetheless, the molecular mechanism by which each EJC component contributes to...
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Full title
eIF4AIII enhances translation of nuclear cap-binding complex–bound mRNAs by promoting disruption of secondary structures in 5′UTR
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4217471
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4217471
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1409695111
