Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia
Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia
About this item
Full title
Author / Creator
Efanov, A , Zanesi, N , Coppola, V , Nuovo, G , Bolon, B , Wernicle-Jameson, D , Lagana, A , Hansjuerg, A , Pichiorri, F and Croce, C M
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
T-cell acute lymphoblastic leukemia (T-ALL) is a neoplasia of thymocytes characterized by the rapid accumulation of the precursors of T lymphocytes.
HMGA2
(high-mobility group AT-hook 2) gene expression is extremely low in normal adult tissues, but it is overexpressed in many tumors. To identify the biological function of HMGA2, we generated...
Alternative Titles
Full title
Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4219444
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4219444
Other Identifiers
ISSN
2044-5385
E-ISSN
2044-5385
DOI
10.1038/bcj.2014.46
