Myeloid expression of angiotensin-converting enzyme facilitates myeloid maturation and inhibits the...
Myeloid expression of angiotensin-converting enzyme facilitates myeloid maturation and inhibits the development of myeloid-derived suppressor cells
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Publisher
New York: Elsevier Inc
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Language
English
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Publisher
New York: Elsevier Inc
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Contents
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells which accumulate in cancer, infection and chronic inflammation. These cells suppress T-cell function and the immune response. Angiotensin-converting enzyme (ACE) is a peptidase that is now known to regulate aspects of myelopoiesis. Here, we show that A...
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Full title
Myeloid expression of angiotensin-converting enzyme facilitates myeloid maturation and inhibits the development of myeloid-derived suppressor cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4221240
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4221240
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ISSN
0023-6837
E-ISSN
1530-0307
DOI
10.1038/labinvest.2014.41
