Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preim...
Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro
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Author / Creator
Natesan, Senthilkumar A. , Bladon, Alex J. , Coskun, Serdar , Qubbaj, Wafa , Prates, Renata , Munne, Santiago , Coonen, Edith , Dreesen, Joseph C.F.M. , Stevens, Servi J.C. , Paulussen, Aimee D.C. , Stock-Myer, Sharyn E. , Wilton, Leeanda J. , Jaroudi, Souraya , Wells, Dagan , Brown, Anthony P.C. and Handyside, Alan H.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Purpose:
Our aim was to compare the accuracy of family- or disease-specific targeted haplotyping and direct mutation-detection strategies with the accuracy of genome-wide mapping of the parental origin of each chromosome, or karyomapping, by single-nucleotide polymorphism genotyping of the parents, a close relative of known disease status, and t...
Alternative Titles
Full title
Genome-wide karyomapping accurately identifies the inheritance of single-gene defects in human preimplantation embryos in vitro
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4225458
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4225458
Other Identifiers
ISSN
1098-3600
E-ISSN
1530-0366
DOI
10.1038/gim.2014.45
