FLT3 and CDK4/6 inhibitors: Signaling mechanisms and tumor burden in subcutaneous and orthotopic mou...
FLT3 and CDK4/6 inhibitors: Signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemia
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Publisher
Boston: Springer US
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Language
English
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Publisher
Boston: Springer US
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Contents
FLT3
ITD
subtype acute myeloid leukemia (AML) has a poor prognosis with currently available therapies. A number of small molecule inhibitors of FLT3 and/or CDK4/6 are currently under development. A more complete and quantitative understanding of the mechanisms of action of FLT3 and CDK4/6 inhibitors may better inform the development of curren...
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Full title
FLT3 and CDK4/6 inhibitors: Signaling mechanisms and tumor burden in subcutaneous and orthotopic mouse models of acute myeloid leukemia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4226810
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4226810
Other Identifiers
ISSN
1567-567X
E-ISSN
1573-8744
DOI
10.1007/s10928-014-9393-x