PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner
PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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This study was aimed to determine the role and regulation of progranulin (PGRN) in the pathogenesis of inflammatory bowel diseases (IBD). Dextran sulfate sodium (DSS)−, picrylsulfonic acid (TNBS)-induced, bone marrow chimera and CD4+CD45Rb
hi
T cell transfer colitis model were established and analyzed in wild-type and several genetically-modi...
Alternative Titles
Full title
PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4228332
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4228332
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep07023
