Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis
Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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β
2
-adrenergic receptor–mediated cAMP signaling from internal compartments is more effective compared to the plasma membrane in regulating a distinct set of genes, demonstrating a functional significance for the spatial separation of cAMP signaling.
G protein–coupled receptors (GPCRs) are well known to signal via cyclic AMP (cAMP) product...
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Full title
Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4232470
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4232470
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ISSN
1552-4450
E-ISSN
1552-4469
DOI
10.1038/nchembio.1665