Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease
Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease
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Full title
Author / Creator
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Alzheimer's disease (AD) is a devastating disease characterized by synaptic and neuronal loss in the elderly. Compelling evidence suggests that soluble amyloid-β peptide (Aβ) oligomers induce synaptic loss in AD. Aβ-induced synaptic dysfunction is dependent on overstimulation of N-methyl-D-aspartate receptors (NMDARs) resulting in aberrant activati...
Alternative Titles
Full title
Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4237769
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4237769
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/1750-1326-9-48
