HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β
HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cellular DNA repair processes are crucial to maintain genome stability and integrity. In DNA base excision repair, a tight heterodimer complex formed by DNA polymerase β (Polβ) and XRCC1 is thought to facilitate repair by recruiting Polβ to DNA damage sites. Here we show that disruption of the complex does not impact DNA damage response or DNA repa...
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Full title
HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4246423
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4246423
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms6513
