ABCB5 is a limbal stem cell gene required for corneal development and repair
ABCB5 is a limbal stem cell gene required for corneal development and repair
About this item
Full title
Author / Creator
Ksander, Bruce R. , Kolovou, Paraskevi E. , Wilson, Brian J. , Saab, Karim R. , Guo, Qin , Ma, Jie , McGuire, Sean P. , Gregory, Meredith S. , Vincent, William J. B. , Perez, Victor L. , Cruz-Guilloty, Fernando , Kao, Winston W. Y. , Call, Mindy K. , Tucker, Budd A. , Zhan, Qian , Murphy, George F. , Lathrop, Kira L. , Alt, Clemens , Mortensen, Luke J. , Lin, Charles P. , Zieske, James D. , Frank, Markus H. and Frank, Natasha Y.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The loss of limbal stem cells (LSCs) due to injury or disease is one of the leading causes of blindness; here, the ABCB5 protein is identified as a marker of LSCs in mouse and human eye, and shown to be functionally required for LSC maintenance, corneal development and repair.
ABCB5
gene in corneal development and repair
The limbal stem ce...
Alternative Titles
Full title
ABCB5 is a limbal stem cell gene required for corneal development and repair
Authors, Artists and Contributors
Author / Creator
Kolovou, Paraskevi E.
Wilson, Brian J.
Saab, Karim R.
Guo, Qin
Ma, Jie
McGuire, Sean P.
Gregory, Meredith S.
Vincent, William J. B.
Perez, Victor L.
Cruz-Guilloty, Fernando
Kao, Winston W. Y.
Call, Mindy K.
Tucker, Budd A.
Zhan, Qian
Murphy, George F.
Lathrop, Kira L.
Alt, Clemens
Mortensen, Luke J.
Lin, Charles P.
Zieske, James D.
Frank, Markus H.
Frank, Natasha Y.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4246512
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4246512
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13426
