Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding
Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Significance Bone morphogenetic proteins (BMPs) are essential signaling molecules important in embryo development and maintaining tissue function in adulthood. BMPs are regulated outside the cell by inhibitors such as chordin. The structure of chordin is unknown as extracellular proteins are generally not suitable for high-resolution methods. This...
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Full title
Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4246984
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4246984
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1404166111