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NOTCH‐Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Desig...

NOTCH‐Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Desig...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4250205

NOTCH‐Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine

About this item

Full title

NOTCH‐Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine

Publisher

Durham, NC, USA: AlphaMed Press

Journal title

Stem cells translational medicine, 2014-12, Vol.3 (12), p.1456-1466

Language

English

Formats

Publication information

Publisher

Durham, NC, USA: AlphaMed Press

More information

Scope and Contents

Contents

This work examines a novel biological method that entails selection of human bone marrow‐derived stromal/stem cells (BMSCs) based on NOTCH2 expression and activation of the NOTCH signaling pathway in cultured BMSCs via a tissue culture plate coated with recombinant human JAGGED1 (JAG1) ligand. We demonstrate that transient JAG1‐mediated NOTCH signa...

Alternative Titles

Full title

NOTCH‐Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4250205

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4250205

Other Identifiers

ISSN

2157-6564

E-ISSN

2157-6580

DOI

10.5966/sctm.2014-0034

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